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The Structure of DC-SIGNR with a Portion of its Repeat Domain Lends Insights to Modeling of the Receptor Tetramer

The dendritic cell-specific ICAM-3 non-integrin (DC-SIGN) and its close relative DC-SIGNR recognize various glycoproteins, both pathogenic and cellular, through the receptor lectin domain-mediated carbohydrate recognition. While the carbohydrate-recognition domains (CRD) exist as monomers and bind i...

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Detalles Bibliográficos
Autores principales: Snyder, Greg A., Colonna, Marco, Sun, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094344/
https://www.ncbi.nlm.nih.gov/pubmed/15784257
http://dx.doi.org/10.1016/j.jmb.2005.01.063