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Development of inhibitors in the ubiquitination cascade

The ubiquitin proteasome system (UPS) is essential in regulating myriad aspects of protein functions. It is therefore a fundamentally important regulatory mechanism that impacts most if not all aspects of cellular processes. Indeed, malfunction of UPS components is implicated in human diseases such...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Sidhu, Sachdev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094371/
https://www.ncbi.nlm.nih.gov/pubmed/24239534
http://dx.doi.org/10.1016/j.febslet.2013.11.003