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Inhibition of SIRT1 by microRNA-9, the key point in process of LPS-induced severe inflammation

Severe inflammation may lead to multiple organs dysfunction syndrome, which has a high mortality. MicroRNA is found participated in this process. In this study we developed a lipopolysaccharide-induced inflammation cell model on macrophages and a lipopolysaccharide-induced inflammation mouse model....

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Detalles Bibliográficos
Autores principales: Cao, Mengyuan, Zhang, Wanfu, Li, Junjie, Zhang, Julei, Li, Lincheng, Liu, Mingchuan, Yin, Wen, Bai, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094484/
https://www.ncbi.nlm.nih.gov/pubmed/30552873
http://dx.doi.org/10.1016/j.abb.2018.12.016