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Differential effects of triptolide and tetrandrine on activation of COX-2, NF-κB, and AP-1 and virus production in dengue virus-infected human lung cells

Most virus infections induce cycloxygenase-2 (COX-2) expression and subsequent prostaglandin E(2) (PGE(2)) production in cells, an inflammatory response that might be detrimental to virus replication and pathogenesis. This response in dengue virus infection remains to be elucidated. Triptolide and t...

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Detalles Bibliográficos
Autores principales: Liou, Jun-Ting, Chen, Zih-Yan, Ho, Ling-Jun, Yang, Shih-Ping, Chang, Deh-Ming, Liang, Chun-Chin, Lai, Jenn-Haung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094504/
https://www.ncbi.nlm.nih.gov/pubmed/18565510
http://dx.doi.org/10.1016/j.ejphar.2008.04.056