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Structure and Cleavage Specificity of the Chymotrypsin-Like Serine Protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

Biogenesis and replication of the porcine reproductive and respiratory syndrome virus (PRRSV) include the crucial step of replicative polyprotein processing by self-encoded proteases. Whole genome bioinformatics analysis suggests that nonstructural protein 4 (nsp4) is a 3C-like serine protease (3CLS...

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Detalles Bibliográficos
Autores principales: Tian, Xinsheng, Lu, Guangwen, Gao, Feng, Peng, Hao, Feng, Youjun, Ma, Guangpeng, Bartlam, Mark, Tian, Kegong, Yan, Jinghua, Hilgenfeld, Rolf, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094510/
https://www.ncbi.nlm.nih.gov/pubmed/19646449
http://dx.doi.org/10.1016/j.jmb.2009.07.062