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Structure and Cleavage Specificity of the Chymotrypsin-Like Serine Protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Biogenesis and replication of the porcine reproductive and respiratory syndrome virus (PRRSV) include the crucial step of replicative polyprotein processing by self-encoded proteases. Whole genome bioinformatics analysis suggests that nonstructural protein 4 (nsp4) is a 3C-like serine protease (3CLS...
Autores principales: | Tian, Xinsheng, Lu, Guangwen, Gao, Feng, Peng, Hao, Feng, Youjun, Ma, Guangpeng, Bartlam, Mark, Tian, Kegong, Yan, Jinghua, Hilgenfeld, Rolf, Gao, George F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094510/ https://www.ncbi.nlm.nih.gov/pubmed/19646449 http://dx.doi.org/10.1016/j.jmb.2009.07.062 |
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