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Negative regulation of TBK1‐mediated antiviral immunity
TANK‐binding kinase 1 (TBK1) plays pivotal roles in antiviral innate immunity. TBK1 mediates the activation of interferon regulatory factor (IRF) 3, leading to the induction of type I IFNs (IFN‐α/β) following viral infections. TBK1 must be tightly regulated to effectively control viral infections an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094513/ https://www.ncbi.nlm.nih.gov/pubmed/23395611 http://dx.doi.org/10.1016/j.febslet.2013.01.052 |