ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations

ORF8a protein is 39 residues long and contains a single transmembrane domain. The protein is synthesized using solid phase peptide synthesis and reconstituted into artificial lipid bilayers that forms cation-selective ion channels with a main conductance level of 8.9 ± 0.8 pS at elevated temperature...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Chang, Krüger, Jens, Sramala, Issara, Hsu, Hao-Jen, Henklein, Peter, Chen, Yi-Ming Arthur, Fischer, Wolfgang B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094593/
https://www.ncbi.nlm.nih.gov/pubmed/20708597
http://dx.doi.org/10.1016/j.bbamem.2010.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094593/
https://www.ncbi.nlm.nih.gov/pubmed/20708597
http://dx.doi.org/10.1016/j.bbamem.2010.08.004

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