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ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations
ORF8a protein is 39 residues long and contains a single transmembrane domain. The protein is synthesized using solid phase peptide synthesis and reconstituted into artificial lipid bilayers that forms cation-selective ion channels with a main conductance level of 8.9 ± 0.8 pS at elevated temperature...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094593/ https://www.ncbi.nlm.nih.gov/pubmed/20708597 http://dx.doi.org/10.1016/j.bbamem.2010.08.004 |