Fast, selective and quantitative protein profiling of adenovirus-vector based vaccines by ultra-performance liquid chromatography

A method for the quantitative determination of the protein composition of adenovirus-vector based vaccines was developed. The final method used RP-UPLC with UV absorbance detection, a C4 column (300 Å, 1.7 μm, 2.1 × 150 mm), and a water- acetonitrile (ACN) gradient containing trifluoroacetic acid (T...

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Detalles Bibliográficos
Autores principales: van Tricht, Ewoud, de Raadt, Pascal, Verwilligen, Annemiek, Schenning, Martijn, Backus, Harold, Germano, Marta, Somsen, Govert W., Sänger-van de Griend, Cari E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094600/
https://www.ncbi.nlm.nih.gov/pubmed/30389208
http://dx.doi.org/10.1016/j.chroma.2018.10.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094600/
https://www.ncbi.nlm.nih.gov/pubmed/30389208
http://dx.doi.org/10.1016/j.chroma.2018.10.045

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