Immunization with a poly (lactide co-glycolide) encapsulated plasmid DNA expressing antigenic regions of HPV 16 and 18 results in an increase in the precursor frequency of T cells that respond to epitopes from HPV 16, 18, 6 and 11

A phase II trial was conducted in subjects with human papillomavirus (HPV) associated high-grade cervical dysplasia testing the safety and efficacy of a microparticle encapsulated pDNA vaccine. Amolimogene expresses T cell epitopes from E6 and E7 proteins of HPV types 16 and 18. An analysis was perf...

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Detalles Bibliográficos
Autores principales: Matijevic, Mark, Hedley, Mary Lynne, Urban, Robert G., Chicz, Roman M., Lajoie, Christa, Luby, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094646/
https://www.ncbi.nlm.nih.gov/pubmed/21550027
http://dx.doi.org/10.1016/j.cellimm.2011.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094646/
https://www.ncbi.nlm.nih.gov/pubmed/21550027
http://dx.doi.org/10.1016/j.cellimm.2011.04.005

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