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Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS‐associated coronavirus

SARS‐associated coronavirus was identified as the etiological agent of severe acute respiratory syndrome and a large virus pool was identified in wild animals. Virus generates drug resistance through fast mutagenesis and escapes antiviral treatment. siRNAs targeting different genes would be an alter...

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Detalles Bibliográficos
Autores principales: He, Ming-Liang, Zheng, Bo-jian, Chen, Ying, Wong, Kin-Ling, Huang, Jian-Dong, Lin, Marie C., Peng, Ying, Yuen, Kwok Y., Sung, Joseph J.Y., Kung, Hsiang-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094648/
https://www.ncbi.nlm.nih.gov/pubmed/16638566
http://dx.doi.org/10.1016/j.febslet.2006.03.066