Saikosaponin b2 enhances the hepatotargeting effect of anticancer drugs through inhibition of multidrug resistance-associated drug transporters

Aims: Vinegar-baked Radix Bupleuri (VBRB) potentiates the activity of anticancer drugs in the liver by increasing their hepatic distribution. However, this phenomenon may be associated with drug transporters. We investigated the effect of saikosaponin b2 (SSb2; the main component of VBRB) on the act...

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Detalles Bibliográficos
Autores principales: Zhao, Ya, Feng, Limin, Liu, Lijuan, Zhao, Ruizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094655/
https://www.ncbi.nlm.nih.gov/pubmed/31194994
http://dx.doi.org/10.1016/j.lfs.2019.116557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094655/
https://www.ncbi.nlm.nih.gov/pubmed/31194994
http://dx.doi.org/10.1016/j.lfs.2019.116557

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