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Interaction of the Dengue Virus Fusion Peptide with Membranes Assessed by NMR: The Essential Role of the Envelope Protein Trp101 for Membrane Fusion

Dengue virus (DV) infection depends on a step of membrane fusion, which occurs in the acidic environment of the endosome. This process is mediated by virus surface envelope glycoprotein, in which the loop between residues D98–G112 is considered to be crucial, acting as a fusion peptide. Here, we hav...

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Detalles Bibliográficos
Autores principales: Melo, Manuel Nuno, Sousa, Francisco J.R., Carneiro, Fabiana A., Castanho, Miguel A.R.B., Valente, Ana Paula, Almeida, Fabio C.L., Da Poian, Andrea T., Mohana-Borges, Ronaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094664/
https://www.ncbi.nlm.nih.gov/pubmed/19619560
http://dx.doi.org/10.1016/j.jmb.2009.07.035