BiP/GRP78 Mediates ERAD Targeting of Proteins Produced by Membrane-Bound Ribosomes Stalled at the STOP-Codon

Translational stalling of ribosome bound to endoplasmic reticulum (ER) membrane requires an accurate clearance of the associated polypeptides, which is not completely understood in mammals. We characterized in mammalian cells the model of ribosomal stalling at the STOP-codon based on proteins tagged...

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Detalles Bibliográficos
Autores principales: Cesaratto, Francesca, Sasset, Linda, Myers, Michael P., Re, Angela, Petris, Gianluca, Burrone, Oscar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094721/
https://www.ncbi.nlm.nih.gov/pubmed/30367842
http://dx.doi.org/10.1016/j.jmb.2018.10.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094721/
https://www.ncbi.nlm.nih.gov/pubmed/30367842
http://dx.doi.org/10.1016/j.jmb.2018.10.009

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