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Pre-structured hydrophobic peptide β-strands: A universal amyloid trap?

Amyloid fibril formation has long been studied because of the variety of proteins that are capable of adopting this structure despite sharing little sequence homology. This makes amyloid fibrils a challenging focus for inhibition studies because the peptides and proteins that form amyloid fibrils ca...

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Detalles Bibliográficos
Autores principales: Sivanesam, Kalkena, Andersen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094768/
https://www.ncbi.nlm.nih.gov/pubmed/30707943
http://dx.doi.org/10.1016/j.abb.2019.01.032