Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress

Mycobacterium abscessus (MAB) is a rapidly growing mycobacterium (RGM), and infections with this pathogen have been increasing worldwide. Recently, we reported that rough type (MAB-R) but not smooth type (MAB-S) strains enhanced type 1 interferon (IFN-I) secretion via bacterial phagosome escape, con...

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Detalles Bibliográficos
Autores principales: Kim, Bo-Ram, Kim, Byoung-Jun, Kook, Yoon-Hoh, Kim, Bum-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094820/
https://www.ncbi.nlm.nih.gov/pubmed/32210476
http://dx.doi.org/10.1371/journal.ppat.1008294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094820/
https://www.ncbi.nlm.nih.gov/pubmed/32210476
http://dx.doi.org/10.1371/journal.ppat.1008294

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