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An in-silico human cell model reveals the influence of spatial organization on RNA splicing
Spatial organization is a characteristic of all cells, achieved in eukaryotic cells by utilizing both membrane-bound and membrane-less organelles. One of the key processes in eukaryotes is RNA splicing, which readies mRNA for translation. This complex and highly dynamical chemical process involves a...
Autores principales: | Ghaemi, Zhaleh, Peterson, Joseph R., Gruebele, Martin, Luthey-Schulten, Zaida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094823/ https://www.ncbi.nlm.nih.gov/pubmed/32210422 http://dx.doi.org/10.1371/journal.pcbi.1007717 |
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