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Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels

Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis. However, this targeted approach has to date been unable to identify major regulators of cell-to-cell g...

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Detalles Bibliográficos
Autores principales: Morgan, Michael D., Patin, Etienne, Jagla, Bernd, Hasan, Milena, Quintana-Murci, Lluís, Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094872/
https://www.ncbi.nlm.nih.gov/pubmed/32168362
http://dx.doi.org/10.1371/journal.pgen.1008686