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Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis. However, this targeted approach has to date been unable to identify major regulators of cell-to-cell g...
Autores principales: | Morgan, Michael D., Patin, Etienne, Jagla, Bernd, Hasan, Milena, Quintana-Murci, Lluís, Marioni, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094872/ https://www.ncbi.nlm.nih.gov/pubmed/32168362 http://dx.doi.org/10.1371/journal.pgen.1008686 |
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