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Lack of nitric oxide synthase type 2 (NOS2) results in reduced neuronal apoptosis and mortality following mouse hepatitis virus infection of the central nervous system

The role of nitric oxide synthase type-2 (NOS2)-derived nitric oxide (NO) in the pathogenesis of mouse hepatitis virus (MHV)-induced central nervous system disease was examined. Infection of NOS2 knockout ((−/−)) and NOS2(+/+) mice with MHV resulted in similar kinetics of viral clearance from the br...

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Detalles Bibliográficos
Autores principales: Chen, Benjamin P., Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094997/
https://www.ncbi.nlm.nih.gov/pubmed/11847593
http://dx.doi.org/10.1080/135502802317247820