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Lack of nitric oxide synthase type 2 (NOS2) results in reduced neuronal apoptosis and mortality following mouse hepatitis virus infection of the central nervous system
The role of nitric oxide synthase type-2 (NOS2)-derived nitric oxide (NO) in the pathogenesis of mouse hepatitis virus (MHV)-induced central nervous system disease was examined. Infection of NOS2 knockout ((−/−)) and NOS2(+/+) mice with MHV resulted in similar kinetics of viral clearance from the br...
Autores principales: | Chen, Benjamin P., Lane, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094997/ https://www.ncbi.nlm.nih.gov/pubmed/11847593 http://dx.doi.org/10.1080/135502802317247820 |
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