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Neither B cells nor T cells are required for CNS demyelination in mice persistently infected with MHV-A59
Murine hepatitis virus A59 infection of the central nervous system (CNS) results in CNS demyelination in susceptible strains of mice. In infected B-cell-deficient mice, demyelination not only occurred but was also more severe than in parental C57BL/6 animals. This increase may be due to the persiste...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095043/ https://www.ncbi.nlm.nih.gov/pubmed/12053280 http://dx.doi.org/10.1080/13550280290049697 |