Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4

Mouse hepatitis virus type 4 (MHV-4, the JHM strain), a positive-strand RNA virus of the coronavirus family, is well documented as an inducer of acute(1–4) and chronic(5,6) demyelination in mice, as well as subacute demyelination in rats(7,8), due to a cytolytic infection of oligodendrocytes(3,4,7)....

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Detalles Bibliográficos
Autores principales: Knobler, Robert L., Lampert, Peter W., Oldstone, Michael B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 1982
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095068/
https://www.ncbi.nlm.nih.gov/pubmed/6283382
http://dx.doi.org/10.1038/298279a0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095068/
https://www.ncbi.nlm.nih.gov/pubmed/6283382
http://dx.doi.org/10.1038/298279a0

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