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Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4
Mouse hepatitis virus type 4 (MHV-4, the JHM strain), a positive-strand RNA virus of the coronavirus family, is well documented as an inducer of acute(1–4) and chronic(5,6) demyelination in mice, as well as subacute demyelination in rats(7,8), due to a cytolytic infection of oligodendrocytes(3,4,7)....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095068/ https://www.ncbi.nlm.nih.gov/pubmed/6283382 http://dx.doi.org/10.1038/298279a0 |