Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence

The spike (S) glycoprotein of mouse hepatitis virus (MHV) is a major determinant of neurovirulence. Using targeted recombination we previously demonstrated that the S gene of the highly neurovirulent MHV-4 conferred a dramatic increase in neurovirulence to the mildly neurovirulent MHV-A59. To identi...

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Detalles Bibliográficos
Autores principales: Phillips, Joanna J., Chua, MingMing, Seo, Su-hun, Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095106/
https://www.ncbi.nlm.nih.gov/pubmed/11582514
http://dx.doi.org/10.1080/135502801753170273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095106/
https://www.ncbi.nlm.nih.gov/pubmed/11582514
http://dx.doi.org/10.1080/135502801753170273

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