Sequence analysis of the S gene of recombinant MHV-2/A59 coronaviruses reveals three candidate mutations associated with demyelination and hepatitis

Coronaviruses, mouse hepatitis virus (MHV) strains, exhibit various degrees of neurotropism and hepatotropism following intracerebral (IC) infection of 4-week-old C57Bl/6 mice. Whereas MHV-A59 produces acute meningitis, encephalitis, hepatitis, and chronic demyelination, a closely related strain, MH...

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Detalles Bibliográficos
Autores principales: Das Sarma, Jayasri, Fu, Li, Hingley, Susan T., Lai, Michael M. C., Lavi, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095204/
https://www.ncbi.nlm.nih.gov/pubmed/11582515
http://dx.doi.org/10.1080/135502801753170282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095204/
https://www.ncbi.nlm.nih.gov/pubmed/11582515
http://dx.doi.org/10.1080/135502801753170282

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