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Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430

Filoviruses are emerging pathogens and causative agents of viral haemorrhagic fever. Case fatality rates of filovirus disease outbreaks are among the highest reported for any human pathogen, exceeding 90% (ref. 1). Licensed therapeutic or vaccine products are not available to treat filovirus disease...

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Detalles Bibliográficos
Autores principales: Warren, Travis K., Wells, Jay, Panchal, Rekha G., Stuthman, Kelly S., Garza, Nicole L., Van Tongeren, Sean A., Dong, Lian, Retterer, Cary J., Eaton, Brett P., Pegoraro, Gianluca, Honnold, Shelley, Bantia, Shanta, Kotian, Pravin, Chen, Xilin, Taubenheim, Brian R., Welch, Lisa S., Minning, Dena M., Babu, Yarlagadda S., Sheridan, William P., Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095208/
https://www.ncbi.nlm.nih.gov/pubmed/24590073
http://dx.doi.org/10.1038/nature13027