A combination of mutations in the S1 part of the spike glycoprotein gene of coronavirus MHV-A59 abolishes demyelination

The A59 strain of coronavirus, mouse hepatitis virus (MHV), produces acute hepatitis, meningoencephalitis, and chronic demyelination. The authors have previously shown that the spike (S) glycoprotein gene of MHV contains determinants of virulence, hepatitis, and demyelination. They then identified v...

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Detalles Bibliográficos
Autores principales: Fu, Li, Gonzales, Donna M., Das Sarma, Jayasri, Lavi, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095319/
https://www.ncbi.nlm.nih.gov/pubmed/14982727
http://dx.doi.org/10.1080/13550280490262229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095319/
https://www.ncbi.nlm.nih.gov/pubmed/14982727
http://dx.doi.org/10.1080/13550280490262229

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