An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

Passive serotherapy can confer immediate protection against microbial infection, but methods to rapidly generate human neutralizing monoclonal antibodies are not yet available. We have developed an improved method for Epstein-Barr virus transformation of human B cells. We used this method to analyze...

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Detalles Bibliográficos
Autores principales: Traggiai, Elisabetta, Becker, Stephan, Subbarao, Kanta, Kolesnikova, Larissa, Uematsu, Yasushi, Gismondo, Maria Rita, Murphy, Brian R, Rappuoli, Rino, Lanzavecchia, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095806/
https://www.ncbi.nlm.nih.gov/pubmed/15247913
http://dx.doi.org/10.1038/nm1080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095806/
https://www.ncbi.nlm.nih.gov/pubmed/15247913
http://dx.doi.org/10.1038/nm1080

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