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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase
Leukotoxin is a linoleic acic oxide produced by leukocytes and has been associated with the multiple organ failure and adult respiratory distress syndrome seen in some severe burn patients. Leukotoxin has been reported to be toxic when injected into animals intravenously. Herein, we report that this...
Autores principales: | Moghaddam, Mehran F., Grant, David F., Cheek, Jeffrey M., Greene, Jessica F., Williamson, Kristin C., Hammock, Bruce D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095900/ https://www.ncbi.nlm.nih.gov/pubmed/9142128 http://dx.doi.org/10.1038/nm0597-562 |
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