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gp41: HIV's shy protein

The first X-ray crystal structures of gp41, the protein that mediates fusion of HIV-1 to target cells, were solved in the mid-1990s. The structures provide a foundation for understanding viral entry and the mechanism of action of compounds that block fusion. The first fusion inhibitor has recently e...

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Detalles Bibliográficos
Autores principales: Zwick, Michael B, Saphire, Erica O, Burton, Dennis R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095992/
https://www.ncbi.nlm.nih.gov/pubmed/14760422
http://dx.doi.org/10.1038/nm0204-133