The insulator functions of the Drosophila polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency

In mammals, a C2H2 zinc finger (C2H2) protein, CTCF, acts as the master regulator of chromosomal architecture and of the expression of Hox gene clusters. Like mammalian CTCF, the Drosophila homolog, dCTCF, localizes to boundaries in the bithorax complex (BX-C). Here, we have determined the minimal r...

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Detalles Bibliográficos
Autores principales: Kyrchanova, Olga, Maksimenko, Oksana, Ibragimov, Airat, Sokolov, Vladimir, Postika, Nikolay, Lukyanova, Maria, Schedl, Paul, Georgiev, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096168/
https://www.ncbi.nlm.nih.gov/pubmed/32232161
http://dx.doi.org/10.1126/sciadv.aaz3152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096168/
https://www.ncbi.nlm.nih.gov/pubmed/32232161
http://dx.doi.org/10.1126/sciadv.aaz3152

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