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DirectMX – One-Step Reconstitution of Membrane Proteins From Crude Cell Membranes Into Salipro Nanoparticles

Integral membrane proteins (IMPs) are central to many physiological processes and represent ∼60% of current drug targets. An intricate interplay with the lipid molecules in the cell membrane is known to influence the stability, structure and function of IMPs. Detergents are commonly used to solubili...

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Detalles Bibliográficos
Autores principales: Lloris-Garcerá, Pilar, Klinter, Stefan, Chen, Liuhong, Skynner, Michael J., Löving, Robin, Frauenfeld, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096351/
https://www.ncbi.nlm.nih.gov/pubmed/32266242
http://dx.doi.org/10.3389/fbioe.2020.00215