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DirectMX – One-Step Reconstitution of Membrane Proteins From Crude Cell Membranes Into Salipro Nanoparticles
Integral membrane proteins (IMPs) are central to many physiological processes and represent ∼60% of current drug targets. An intricate interplay with the lipid molecules in the cell membrane is known to influence the stability, structure and function of IMPs. Detergents are commonly used to solubili...
Autores principales: | Lloris-Garcerá, Pilar, Klinter, Stefan, Chen, Liuhong, Skynner, Michael J., Löving, Robin, Frauenfeld, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096351/ https://www.ncbi.nlm.nih.gov/pubmed/32266242 http://dx.doi.org/10.3389/fbioe.2020.00215 |
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