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Cardiac specific transcription factor Csx/Nkx2.5 regulates transient-outward K(+) channel expression in pluripotent P19 cell-derived cardiomyocytes

The homeobox-containing gene Csx/Nkx2.5 codes several cardiac transcription factors and plays a critical role in early cardiogenesis. We investigated the effect of Csx/Nkx2.5 on the expression of cardiac ion channels using P19-derived cardiomyocytes. P19CL6 cells and P19CL6 cells with Csx/Nkx2.5 ove...

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Detalles Bibliográficos
Autores principales: Uchino, Tomoko, Zheng, Ming-Qi, Wang, Yan, Ono, Katsushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096375/
https://www.ncbi.nlm.nih.gov/pubmed/32213161
http://dx.doi.org/10.1186/s12576-020-00748-z