The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P(2) facilitating unconventional secretion of Fibroblast Growth Factor 2

FGF2 is a tumor cell survival factor that is exported from cells by an ER/Golgi-independent secretory pathway. This unconventional mechanism of protein secretion is based on direct translocation of FGF2 across the plasma membrane. The Na,K-ATPase has previously been shown to play a role in this proc...

Descripción completa

Detalles Bibliográficos
Autores principales: Legrand, Cyril, Saleppico, Roberto, Sticht, Jana, Lolicato, Fabio, Müller, Hans-Michael, Wegehingel, Sabine, Dimou, Eleni, Steringer, Julia P., Ewers, Helge, Vattulainen, Ilpo, Freund, Christian, Nickel, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096399/
https://www.ncbi.nlm.nih.gov/pubmed/32214225
http://dx.doi.org/10.1038/s42003-020-0871-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096399/
https://www.ncbi.nlm.nih.gov/pubmed/32214225
http://dx.doi.org/10.1038/s42003-020-0871-y

Ejemplares similares