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Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing — Implication for metabolic remodeling

The global incidence of the human nontuberculous mycobacteria (NTM) disease is rapidly increasing. However, knowledge of gene essentiality under optimal growth conditions and conditions relevant to the natural ecology of NTM, such as hypoxia, is lacking. In this study, we utilized transposon sequenc...

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Detalles Bibliográficos
Autores principales: Tateishi, Yoshitaka, Minato, Yusuke, Baughn, Anthony D., Ohnishi, Hiroaki, Nishiyama, Akihito, Ozeki, Yuriko, Matsumoto, Sohkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096427/
https://www.ncbi.nlm.nih.gov/pubmed/32214196
http://dx.doi.org/10.1038/s41598-020-62287-2