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Semi-CAM: A semi-supervised deconvolution method for bulk transcriptomic data with partial marker gene information

Deconvolution of bulk transcriptomics data from mixed cell populations is vital to identify the cellular mechanism of complex diseases. Existing deconvolution approaches can be divided into two major groups: supervised and unsupervised methods. Supervised deconvolution methods use cell type-specific...

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Detalles Bibliográficos
Autores principales: Dong, Li, Kollipara, Avinash, Darville, Toni, Zou, Fei, Zheng, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096458/
https://www.ncbi.nlm.nih.gov/pubmed/32214192
http://dx.doi.org/10.1038/s41598-020-62330-2