A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

Spinal muscular atrophy (SMA) is the most common genetic disease in children. SMA is generally caused by mutations in the gene SMN1. The survival of motor neurons (SMN) complex consists of SMN1, Gemins (2–8), and Strap/Unrip. We previously demonstrated smn1 and gemin5 inhibited tissue regeneration i...

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Detalles Bibliográficos
Autores principales: Pei, Wuhong, Xu, Lisha, Chen, Zelin, Slevin, Claire C., Pettie, Kade P., Wincovitch, Stephen, Burgess, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096462/
https://www.ncbi.nlm.nih.gov/pubmed/32218991
http://dx.doi.org/10.1038/s41536-020-0089-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096462/
https://www.ncbi.nlm.nih.gov/pubmed/32218991
http://dx.doi.org/10.1038/s41536-020-0089-0

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