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A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
Spinal muscular atrophy (SMA) is the most common genetic disease in children. SMA is generally caused by mutations in the gene SMN1. The survival of motor neurons (SMN) complex consists of SMN1, Gemins (2–8), and Strap/Unrip. We previously demonstrated smn1 and gemin5 inhibited tissue regeneration i...
Autores principales: | Pei, Wuhong, Xu, Lisha, Chen, Zelin, Slevin, Claire C., Pettie, Kade P., Wincovitch, Stephen, Burgess, Shawn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096462/ https://www.ncbi.nlm.nih.gov/pubmed/32218991 http://dx.doi.org/10.1038/s41536-020-0089-0 |
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