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Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model

Spinocerebellar ataxia 1 (SCA1) is a devastating neurodegenerative disease associated with cerebellar degeneration and motor deficits. However, many patients also exhibit neuropsychiatric impairments such as depression and apathy; nevertheless, the existence of a causal link between the psychiatric...

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Detalles Bibliográficos
Autores principales: Tichanek, Filip, Salomova, Martina, Jedlicka, Jan, Kuncova, Jitka, Pitule, Pavel, Macanova, Tereza, Petrankova, Zuzana, Tuma, Zdenek, Cendelin, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096488/
https://www.ncbi.nlm.nih.gov/pubmed/32214165
http://dx.doi.org/10.1038/s41598-020-62308-0