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Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling
HIF-1α, an essential transcription factor under hypoxic condition, is indispensable for chondrocytes during skeletal development but its expression and roles in articular chondrocytes are yet to be revealed. We examined HIF-1α protein expression and the hypoxic condition during mouse osteoarthritis...
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Fformat: | Online Erthygl Texto |
Iaith: | English |
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Nature Publishing Group UK
2020
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Mynediad Ar-lein: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096515/ https://www.ncbi.nlm.nih.gov/pubmed/32214220 http://dx.doi.org/10.1038/s41598-020-62463-4 |