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ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma

Long-chain acyl-CoA dehydrogenase (ACADL) is a mitochondrial enzyme that catalyzes the initial step of fatty acid oxidation, but the role of ACADL in tumor biology remains largely unknown. Here, we found that ACADL was frequently downregulated in hepatocellular carcinoma (HCC), and its low expressio...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaofang, Qin, Wenhao, Jiang, Youhai, Yang, Zhishi, Yuan, Bo, Dai, Rongyang, Shen, Hao, Chen, Yao, Fu, Jing, Wang, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096519/
https://www.ncbi.nlm.nih.gov/pubmed/32219176
http://dx.doi.org/10.1038/s41698-020-0111-4