PTPσ Knockdown in Lampreys Impairs Reticulospinal Axon Regeneration and Neuronal Survival After Spinal Cord Injury

Traumatic spinal cord injury (SCI) results in persistent functional deficits due to the lack of axon regeneration within the mammalian CNS. After SCI, chondroitin sulfate proteoglycans (CSPGs) inhibit axon regrowth via putative interactions with the LAR-family protein tyrosine phosphatases, PTPσ and...

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Detalles Bibliográficos
Autores principales: Rodemer, William, Zhang, Guixin, Sinitsa, Isabelle, Hu, Jianli, Jin, Li-qing, Li, Shuxin, Selzer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096546/
https://www.ncbi.nlm.nih.gov/pubmed/32265663
http://dx.doi.org/10.3389/fncel.2020.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096546/
https://www.ncbi.nlm.nih.gov/pubmed/32265663
http://dx.doi.org/10.3389/fncel.2020.00061

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