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ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance

The predominant way in which conventional chemotherapy kills rapidly proliferating cancer cells is the induction of DNA damage. However, chemoresistance remains the main obstacle to therapy effectivity. An increasing number of studies suggest that epithelial-to-mesenchymal transition (EMT) represent...

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Detalles Bibliográficos
Autores principales: Drápela, Stanislav, Bouchal, Jan, Jolly, Mohit Kumar, Culig, Zoran, Souček, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096573/
https://www.ncbi.nlm.nih.gov/pubmed/32266287
http://dx.doi.org/10.3389/fmolb.2020.00036