Establishing Trypanosoma cruzi farnesyl pyrophosphate synthase as a viable target for biosensor driven fragment‐based lead discovery

Procedures for producing and exploring Trypanosoma cruzi farnesyl pyrophosphate synthase (tcFPPS) for surface plasmon resonance (SPR) biosensor‐driven fragment‐based discovery have been established. The method requires functional sensor surfaces with high sensitivity for extended times and appropria...

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Detalles Bibliográficos
Autores principales: Opassi, Giulia, Nordström, Helena, Lundin, Arne, Napolitano, Valeria, Magari, Francesca, Dzus, Tom, Klebe, Gerhard, Danielson, U. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096706/
https://www.ncbi.nlm.nih.gov/pubmed/31994261
http://dx.doi.org/10.1002/pro.3834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096706/
https://www.ncbi.nlm.nih.gov/pubmed/31994261
http://dx.doi.org/10.1002/pro.3834

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