Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

Conditioning chemotherapy is used to deplete hematopoietic stem cells in the recipient’s marrow, facilitating donor cell engraftment. Although effective, a major issue with chemotherapy is the systemic genotoxicity that increases the risk for secondary malignancies. Antibody conjugates targeting hem...

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Detalles Bibliográficos
Autores principales: Srikanthan, Meera A., Humbert, Olivier, Haworth, Kevin G., Ironside, Christina, Rajawat, Yogendra S., Blazar, Bruce R., Palchaudhuri, Rahul, Boitano, Anthony E., Cooke, Michael P., Scadden, David T., Kiem, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096734/
https://www.ncbi.nlm.nih.gov/pubmed/32226796
http://dx.doi.org/10.1016/j.omtm.2020.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096734/
https://www.ncbi.nlm.nih.gov/pubmed/32226796
http://dx.doi.org/10.1016/j.omtm.2020.02.001

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