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Precise and Cost-Effective Nanopore Sequencing for Post-GWAS Fine-Mapping and Causal Variant Identification

Fine-mapping of interesting loci discovered by genome-wide association study (GWAS) is mandatory to pinpoint causal variants. Traditionally, this fine-mapping is completed through increasing the genotyping density at candidate loci, for which imputation is the current standard approach. Although imp...

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Detalles Bibliográficos
Autores principales: Magdy, Tarek, Kuo, Hui–Hsuan, Burridge, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096756/
https://www.ncbi.nlm.nih.gov/pubmed/32203907
http://dx.doi.org/10.1016/j.isci.2020.100971