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Synthesis and evaluation of novel chromanone and quinolinone analogues of uniflorol as anti-leishmanial agents

Within this work, we describe the design and synthesis of a range of novel chromanones and quinolinones, based on natural products reported to possess anti-leishmanial action. The core heterocycles were obtained either via classical or ionic liquid mediated Kabbe condensation in the case of chromano...

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Detalles Bibliográficos
Autores principales: Castro, Helena, Cruz, Tânia, de Aguiar Amaral, Patrícia, da Silva Cardoso, Paula, Alsaffar, Ahmed, Farrell, Patrick, Tomás, Ana M., Barlow, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096758/
https://www.ncbi.nlm.nih.gov/pubmed/32258470
http://dx.doi.org/10.1016/j.heliyon.2020.e03614